martedì 18 marzo 2008

Herpes encephalitis








Findings

Figure 1, Figure 2, Figure 3, and Figure 4: MR images show increased T2 signal along the medial temporal lobe.

Patient was not compliant with the treatment and returned two months later with complaint of headache.

Figure 5: CT (two months later) shows left temporal lobe encephalomalacia.


Diagnosis: Herpes encephalitis


Herpes encephalitis is one of the most common sporadic viral encephalitides. Herpes simplex virus type 1 (HSV-1) accounts for the fulminant necrotizing encephalitis seen in adults, and herpes simplex virus type 2 (HSV-2) is responsible for 80-90% of neonatal and almost all congenital infections. Herpes encephalitis can occur either through retrograde propagation of the latent virus in the peripheral ganglion or reactivation of latent virus in the typical adult infection with HSV-1.

Clinical symptoms may be nonspecific. The most common early symptoms are headache and fever. A wide range of neurological symptoms may be encountered and vary from paresthesias, seizures, and meningeal signs to acute confusion or disorientation. Patients with left temporal damage may show symptoms earlier because of language and intellectual impairment.

Isolated case reports of herpes simplex encephalitis associated with HIV infection can be found in the literature. It is suggested that the neurotoxicity of herpes simplex virus and the CD4+ T cell-independent immune mechanisms are able to produce a variety of classic acute limbic encephalitis or atypical extralimbic lesions.

CT classically reveals hypodensity in the temporal lobes and insular cortex. CT is much less sensitive during early symptom onset. CT may be normal in the first 3-5 days by which time the patient may be comatose. Findings on MR reveal high signal corresponding to edematous changes in the temporal lobe, insula and inferior frontal lobes on T2-weighted images within the first 5 days. MR frequently detects asymmetric bilateral temporal lobe involvement. Typically the basal ganglia are spared on T2-weighted imaging. Foci of hemorrhage may be occasionally identified on MR. MR is preferred for follow-up studies of herpes encephalitis. Herpes encephalitis may cause massive tissue necrosis in later stages.

Prompt therapy with acyclovir stops the virus from replicating. Patients with possible HSV should be given acyclovir 10 mg/kg intravenously every 8 hours. With early treatment, nearly 40% of patients recover without significant neurological deficits; however, untreated patients with HSV-1 have almost a 70% mortality rate. MR can play an important role in early diagnosis and in following disease progression/regression.

15 commenti:

  1. When a part of the brain is deprived of oxygen, cells and neurons in that area become dead, causing encephalomalacia. Sometimes, even a minor cerebral ischemia can occur which only restricts blood flow, but doesn’t completely cut off supply, but it can still cause cerebral softening. Read More At https://hipatient.com/encephalomalacia

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    Risposte
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      Elimina
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      Elimina
  2. I'm so exited to share my testimonies about the Good Work of Dr. Emmanuel who cured my Herpes virus with his herbs, I never thought that I will live on earth before the year runs out. I have been suffering from a deadly Herpes virus (HVS) for the past (4)years now; I had spent a lot of money going from one Hospital to another looking for way to get rid of this disease, the hospital have been my home everyday residence. Constant checks up have been my hobby not until this faithful day, I was searching
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    thank you.

    RispondiElimina
  3. I have been suffering from a deadly disease (Hsv) for the past 3 years now, I had spent a lot of money going from one places to another, from churches to churches, hospitals have been my home every day residence. Constant checks up have been my hobby not until this faithful day, I was searching through the internet, I saw a testimony on how Dr Onokun helped someone in curing his (Hsv) herpes disease, quickly I copied his email which is Dronokunherbalcure@gmail.com just to give him a test I spoke to him, he asked me to do some certain things which I did, he told me that he is going to provide the herbal cure to me, which he did, then he asked me to go for medical checkup after some days after using the herbal cure, behold I was free from the deadly disease, he only asked me to post the testimony through the whole world, faithfully am doing it now, please brothers and sisters, he is great, I owe him in return. if you are having a similar problem just email him on : Dronokunherbalcure@gmail.com

    RispondiElimina
  4. ihave been suffering from a deadly disease (Hsv) for the past 3 years now, I had spent a lIot of money going from one places to another, from churches to churches, hospitals have been my home every day residence. Constant checks up have been my hobby not until this faithful day, I was searching through the internet, I saw a testimony on how Dr Onokun helped someone in curing his (Hsv) herpes disease, quickly I copied his email which is Dronokunherbalcure@gmail.com just to give him a test I spoke to him, he asked me to do some certain things which I did, he told me that he is going to provide the herbal cure to me, which he did, then he asked me to go for medical checkup after some days after using the herbal cure, behold I was free from the deadly disease, he only asked me to post the testimony through the whole world, faithfully am doing it now, please brothers and sisters, he is great, I owe him in return. if you are having a similar problem just email him on : Dronokunherbalcure@gmail.com

    RispondiElimina
  5. I’m very excited to inform everyone that I’m completely cured from HSV1&2 recently. I have used Oregano oil, Coconut oil, Acyclovir, Valacyclovir, Famciclovir, and some other products and it’s really help during my outbreaks but I totally got cured from HSV1&2 with a strong and active herbal medicine ordered from a powerful. herbalist called Dr. Onokun and it completely fought the virus away my nervous system and I tested negative after 14 days of using the herbal medicine. I’m here to let everyone know that herpes virus has a complete cure, I got rid of mine with the help of Dr. Onokun and his herbal exploit. Contact him via email: Dronokunherbalcure@gmail.com

    RispondiElimina
  6. I’m very excited to inform everyone that I’m completely cured from HSV1&2 recently. I have used Oregano oil, Coconut oil, Acyclovir, Valacyclovir, Famciclovir, and some other products and it’s really help during my outbreaks but I totally got cured from HSV1&2 with a strong and active herbal medicine ordered from a powerful. herbalist called Dr. Onokun and it completely fought the virus away my nervous system and I tested negative after 14 days of using the herbal medicine. I’m here to let everyone know that herpes virus has a complete cure, I got rid of mine with the help of Dr. Onokun and his herbal exploit. Contact him via email: Dronokunherbalcure@gmail.com

    RispondiElimina
  7. I’m here to testify about what Dr. Omola did for me. I have been suffering from (GENITAL HERPES VIRUS) disease for the past 3 years and had constant pain and inching, especially in my private part. During the first year, I had faith in God that i would be cured someday.This disease started circulating all over my body and I have been taking treatment from my doctor, few weeks ago I came across a testimony of Mary on the internet testifying about a Man called Dr. Omola on how he cured her from 5 years HSV 2. And she also gave the email address of this man, advise anybody to contact him for help on any kind of diseases that he would be of help, so I emailed him telling him about my (HSV 2) he told me not to worry that I was going to be cured!! Well, I never doubted him I have faith he can cure me too,, Dr. Omola prepared and sent me Healing Oil, Soap, roots and herbs which I took. In the first one week, I started experiencing changes all over me, after four weeks of using his Roots/ Herbs, Oil and Soap, I was totally cured. no more inching , pain on me anymore as Dr. Omola assured me. After some time I went to my doctor to do another test behold the result came out negative. So friends my advise is if you have such disease or know anyone who suffers from it or any other disease like HPV, HBV, HIV, ALS, HBP, CANCER etc. you can contact Dr. Omola for help via dr.omolaherbalhome@gmail.com or whatsapp +2348118116254.

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  9. I am here to give my testimony about Dr Ebhota who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by salami, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr Ehbota cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so happy as i am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact him and get cure from Dr Ebhota healing herbal cure of all kinds of sickness you may have like (1) CANCER,(2) DIABETES,(3) HIV&AIDS,(4) URINARY TRACT INFECTION,(5) CANCER,(6) IMPOTENCE,(7) BARENESS/INFERTILITY(8) DIARRHEA(9) ASTHMA(10)SIMPLEX HERPES AND GENITAL(11)COLD SOREHERPES. he also cure my friend from cervical cancer Email: drebhotasoultion@gmail.com or whatsapp him on +2348089535482

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  10. My health was horrible before I decided to try the Protocol Of taking Dr. Omola pure herbal mixture. I felt there was no hope for my health and I was to try the Protocol, thinking it wouldn’t work because I have visited so many hospital but same result. However, I was convinced by a Instagram friend to try the herbal medicine because I wanted to get rid of Herpes virus. The herbal mixture that was given to me was really quick and easy to take, within 2 week I was fully cured from Herpes. The herbal medicine really work and I will like to share this great doctor contact with you all email him dr.omolaherbalhome@gmail.com or WhatsApp +2348118116254 you won't regret it, I promise.

    RispondiElimina
  11. I am here to give my testimony about Dr Ebhota who helped me.. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by salami, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedies on HERPES and I saw comments of people talking about how Dr Ehbota cured them. When I contacted him he gave me hope and sent Herbal medicine to me that I took for just 2 weeks and it seriously worked for me, my HERPES result came out negative. I am so haas I am sharing this testimony. My advice to you all who thinks that there is no cure for herpes that is Not true just contact him and get cure from Dr Ebhota healing herbal cure of all kinds of sickness you may have like
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    (8) DIARRHEA
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    HERPES. he also cured my friend from cervical cancer Email: drebhotasoultion@gmail.com or whatsapp him on +2348089535482

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  12. Am here to appreciate Dr Oluwale for using his herbal medicine to cure my Herpes virus. since 5 years now I have been living with this virus and it has been giving me challenges, I was so perplexed cause i have been taking several drugs to be cured but all of my effort was in vain, one morning i was browsing through the internet then i saw several testimonies about Dr. Oluwale curing people from Herpes virus and immediately i contacted Dr. Oluwale on his email: droluwaleherbs@gmail.com i told him about my troubles and he told me that he can help and he gave me some instructions and which i rightly followed. so he prepared a herbal medicine for me and sent it to me which i used for 2 weeks and everything was like a dream to me and my Herpes virus was totally gone, my dear viewers online don't be enslaved to the antiviral and other supplementary Orthodox medicine just to help suppress the virus and not a cure I advice why don't you contact him today and be free from your diseases because he is very good and a honest a herbal doctor. contact him via email; droluwaleherbs@gmail.com or WhatsApp/Call him on +2348165160236.
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  13. I've been treating herpes virus for several years with different medications until I saw a post on how a young lady got cured from herpes, Out of desperation I decided to contact him with little or no hope of a solution after taken his herbal medications reluctantly to my biggest surprise I tested negative, God bless you Dr ubarlo drubarlohome@gmail.com or Whatsapp +2348119508814 for his wonderful work

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