martedì 23 dicembre 2008

Brain abscess secondary to frontal osteoma and sinusitis


CT demonstrates a well marginated bone density lesion arising from the anterior left frontal sinus wall and protruding into the sinus lumen (Figure 1). Opacification is present in the superior left frontal sinus consistent with sinusitis (Figure 1). The posterior left frontal sinus wall is dehiscent (Figure 2).
MR demonstrates a multilocular ring enhancing process in the left anterior frontal lobe (Figure 1 and Figure 2). The center of the collection demonstrates high signal on diffusion weighted images (yellow arrows in Figure 6 and Figure 7). The overlying dura enhances as does the adjacent frontal sinus (Figure 4 and Figure 5). Vasogenic edema is present in the surrounding left frontal white matter (Figure 2 and Figure 3).

Diagnosis: Brain abscess secondary to frontal osteoma and sinusitis

Brain abscess is an infectious process which results in high morbidity and mortality if undiagnosed and untreated. In today’s era of antibiotics and refined neurosurgical technique, the major obstacle to successful treatment is delayed diagnosis. Noninvasive diagnostic imaging is critical for diagnosis and is directly responsible for improved patient outcomes in the last 10-15 years.

Brain abscess presents as a rapid developing space occupying syndrome usually beginning with a headache, followed by focal neurological deficit or seizure, and may progress to increased intracranial pressure, nausea,vomiting, and loss of consciousness. Fever is absent in 50% of cases as in this case.

Infection occurs by extension from a direct cranial focus or by hematogenous dissemination from an extracranial source with 50% incidence of each. Mastoiditis is the most common cranial source (30%) followed by sinusitis (15%). Hematogenous seeding accounts for 25%, of which endocarditis is the most common cause. No identified cause is found in 20% of cases. Rare causes include retrograde thrombophlebitis from a facial or dental infection, penetrating trauma, meningitis complication, and surgery.

The typical appearance of brain abscess on CT is a focal round lesion with hypodense center and surrounding vasogenic edema. If contrast is given, ring enhancement is seen. Abscess secondary to mastoiditis occurs in the temporal lobe and sometimes the posterior cranial fossa. Paranasal sinusitis results in frontal lobe location, and hematogenous dissemination usually results in multiple lesions following a vascular distribution.

On MRI, brain abscess demonstrates ring enhancement. Compared to other ring enhancing lesions, abscesses exhibit thinner, more regular, and more homogenously enhancing walls. Often, the cortical wall will be thinner. Classically, the lesion will have a T2 hypointense rim. A critical finding usually seen is central restricted diffusion corresponding to the infection products. Necrotic tumors seldom demonstrate restricted diffusion within the necrotic center. A dominant lesion will often demonstrate contiguous smaller satellite lesions. Another helpful finding is surrounding vasogenic edema which invariably is seen with abscess and neoplasm and rarely seen in other ring enhancing or restricted diffusion lesions such as demyelinating lesions. Lymphoma can be a difficult differential diagnosis as lymphoma usually restricts diffusion, causes vasogenic edema, ring enhances, and can have central necrosis. Clinical history of immunocompromise and location are occasionally helpful to differentiate from abscess.

This patient’s frontal sinus osteoma contributed to the frontal sinusitis and/or intracranial extension of the infection. Paranasal sinus osteomas are benign, asymptomatic bone growths that can rarely have intracranial complications including subdural empyema, abscess, CSF leak, and pneumocephalus. Osteomas demonstrate variable ossification from dense ivory type to a more ground glass appearance.

2 commenti:

  1. Most prostate cancers are adenocarcinomas, cancers that arise in glandular cells of the prostate’s epithelial tissue. Prostate cancers usually progress slowly and produce no symptoms in the initial stages. Eventually, the tumor may enlarge like mine use too, the prostate gland, pressing on the urethra and causing painful or frequent urination and blood in the urine. So I was so uncomfortable with this prostate cancer diseases then I decided to do online search on how to cure cancer because I well have read a lot about herbal medicine,I came across a lot of testimony how Dr Itua cure HIV/herpes then Cancer was listed below the comment.with courage I contacted Dr Itua and he sent me his herbal medicine through Courier service then I was asked to pick it up at my post office which i quickly did. I contacted Dr Itua that i have received my herbal medicine so he instructs me on how to drink it for three weeks and that is how Dr Itua Herbal Medicine cure my prostate Cancer, The treatment takes three weeks and I was cured completely. Dr Itua is a god sent and I thank him every day of my life. Contact him now Whatsapp:+2348149277967.
    He listed to that he can as well cure the following diseases below.... Cerebral Amides. Lung Cancer, Alzheimer's disease,Autism,measles, tetanus, whooping cough, tuberculosis, polio and diphtheria Adrenocortical carcinoma. Alma, Uterine Cancer, Breast Cancer, Allergic diseases. Kidney cancer, Love Spell, Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,
    Dementia.Colo rectal cancer, Lottery Spell, Bladder Cancer, Skin Cancer,Ovarian Cancer,Pancreatic Cancer, HIV /Aids, Herpes, Non-Hodgkin lymphoma, Inflammatory bowel disease, Copd, Diabetes, Hepatitis